Panadol Extra Advance is a fast-acting pain relief medication containing paracetamol and caffeine. It is designed to provide effective relief from headaches, migraines, toothaches, menstrual cramps, and muscular aches. Panadol Extra Advance contains paracetamol and caffeine, which work together to provide fast-acting and reliable pain relief. Adults and children over 12 years can take 1-2 tablets with water every 4-6 hours as needed, but not exceeding 8 tablets in 24 hours.